Glass wool in the injection port liner will provide several benefits:
- The capture of non-volatile materials present in the sample.
- Wiping of the needle when an injection is made, this helps ensure the entire sample is deposited in the liner which in turn can improve precision when looking at peak quantification.
- The glass wool provides a high thermal mass, ensuring rapid vapourisation of the injected sample.
A possible downside with the use of glass wool is that over time the strands can become broken, resulting in an increase in activity, which may adversely affect the peak shape of active compounds. As such, when working with compounds of high activity the use of liners containing glass wool is not recommended.
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